深低温保存羊膜在结膜重建中的临床应用  

The clinical application of preserved human amniotic membrane for conjunctival reconstruction in deep hypothermia

作　　者：刘金陵[1] 卢蓉[1] 

机构地区：[1]中国广州中山医科大学中山眼科中心,510060

出　　处：《美中国际眼科杂志》2001年第3期99-100,共2页

摘　　要：目的 评价深低温保存羊膜移植进行结膜重建的手术疗效,并分析羊膜移植结膜重建手术成功的基本条件和具体手术方法与操作要点。方法 用深低温保存的羊膜治疗43例结膜整形患者。无眼球结膜囊狭窄10例,大面积结膜肿瘤13例,睑球粘连9例,复发性胬肉7例,并尝试对少数病例(4例)义眼座暴露,进行羊膜修补。结果 随诊6～18个月,总治愈率达88.64％,无眼球结膜囊狭窄的治愈率为80％,睑球粘连的治愈率达88.89％,大面积结膜肿瘤和复发性胬肉的治愈率皆为100％,而应用深低温保存羊膜修补义眼座暴露,治愈率只有50％。结论 深低温保存的羊膜是一种有良好发展前景的生物材料,羊膜移植结膜重建术後整形外观良好。在具体实践中,结膜重建的手术效果不仅与羊膜的制备和保存有关,而且受手术方式的选择,手术操作技巧以及术後处理的强烈影响。Objective To evaluate the efficacy of preserved human amniotic membrane for conjunctival reconstruction in deep hypothermia and to analyze the methods of surgery. Methods 43 patients with conjunctivoplasty who underwent preserved amniotic membran transplantation were induded. Preserved human amniotic membrane transplantation was performed on 10 patients without conjunctival sac constriction, 13 patients with large conjunctival tumor, 9 patients with symblepharon, 7 patients with recurrent pterygium and 4 patients with orbital implant exposure. Results 39 cases had satisfactory effects (88.86%) during the follow-up periods of 6~18 months, including 8 patients with conjunctival sac constriction, 13 patients with large conjunctival tumor, 8 patients with symblepharon, 7 patients with recurrent pterygium and 2 patients with orbital implant exposure. Conclusion Preserved human amniotic membrane is a promising biological material. The outlook of patients is good. The effect of transplantation is not only related to the preparation of amniotic membrane, but also is influenced by the surgical procedure, surgical techniques and management after operation.

关 键 词：羊膜移植 结膜重建术 深低温保存 

分 类 号：R779.6[医药卫生—眼科]