减压后脑肿大早期弥散加权和T_2加权MRI的实验研究  

Experimental study of diffussion weighted and T_2-weighted MRI in the early stage of postdecompressive brain bulk enlargement

作　　者：朱儒远[1] 许百男[1] 周定标[1] 安宁豫[2] 张志鉴[3] 

机构地区：[1]解放军总医院神经外科,北京100853 [2]解放军总医院核磁共振室 [3]解放军总医院麻醉科

出　　处：《军医进修学院学报》2001年第4期284-286,共3页Academic Journal of Pla Postgraduate Medical School

摘　　要：目的 :观察减压后脑肿大早期弥散加权和T2 加权MRI的变化过程 ,探讨减压后脑肿大早期是否发生脑水肿。方法 :应用弥散加权和T2 加权MRI对 6只猫作实验前和减压后 2h、4h、6h动态观察。结果 :MRI均显示减压后肿大的脑组织明显向对侧移位 ,且随时间推移 ,移位程度加重 ;减压后 2h ,肿大的脑组织在弥散加权MRI上就呈现为低强度信号区 ;减压后 4h ,肿大的脑组织在T2 加权MRI上才呈现为高信号区。结论 :减压后脑肿大早期 (<2h)Objective:With observation about the change process of DWI and T 2 WI in the early stage of postdecompressive brain bulk enlargement, it is proved whether brain edema occurs Methods:DWI and T 2 WI were performed in 6 cats at four time points (before compression and 2?4?6 hours after decompression) to examine the postdecompressive brain bulk enlargement Results:DWI and T 2 WIshowed that the postdecompressive swollen cerebral tissue shifted increasingly to the contralateral side Within 2 hours after decompression, the hypointensity signal of DWI was observed in the swollen hemisphere Within 4 hours after decompression, the high signal of T 2 WI was observed in the swollen hemisphere Conclusions:The vasogenic edema occured in the early stage (<2 h) of the postdecompressive brain bulk enlargement

关 键 词：脑水肿 磁共振成像 MRI 弥散加权 T2加权 动物实验 

分 类 号：R742.7[医药卫生—神经病学与精神病学]