尾式卟啉-5-氟尿嘧啶及其金属络合物的光谱分析  

Spectral and Antitumor Activity Studies of Tail-porphyin-5-fluorouracil and Their Metallic Manganese Complexes

作　　者：杨秋青[1] 韩士田[1] 张慧娟[1] 

机构地区：[1]河北师范大学实验中心化学系,石家庄050016

出　　处：《分析化学》2001年第12期1379-1383,共5页Chinese Journal of Analytical Chemistry

摘　　要：合成了 2 4种新型的尾式卟啉 5 氟尿嘧啶化合物及其金属锰络合物 ,通过核磁共振氢谱 (NMR)、质谱(MS)、红外光谱 (IR)、紫外光谱 (UV)及元素分析确定了其结构 ,并讨论了 2 4种化合物光谱的关系特征及其规律 ,确定卟啉类配体与金属络合的NMR、IR。24 kinds of novel 5-fluorouracil-porphyrin were synthesized. Their structures have been confirmed by H-1 nuclear magnetic resonance (NMR), infrared (IR), ultraviolet (UV), mass spectrometry (MS) and elemental analysis. The spectral characteristics and chemical shift change regulation of 24 compounds were discussed. (HNMR)-H-1, IR, UV data for these compounds have been systematically summarized and can be used to facilitate structural interpretation of similar compounds.

关 键 词：尾式卟啉 5-氟尿嘧啶 金属锰 核磁共振氢谱 红外光谱 紫外光谱 络合物 分析 抗癌活性 抗代谢药物 

分 类 号：O657.3[理学—分析化学]