正畸过程中牙周韧带细胞增殖能力的实验研究  

Assessment of PDL cell proliferation induced by orthodontic forces

作　　者：韩光丽[1] 程祥荣[1] 沈真祥[1] 贺红[1] 

机构地区：[1]湖北医科大学口腔医学院正畸科,430070

出　　处：《口腔正畸学》2001年第2期82-84,共3页Chinese Journal of Orthodontics

摘　　要：目的　旨在研究正畸力作用下牙齿移动过程中 ,牙周韧带细胞的增殖规律。方法　在兔口腔内安装矫治器 ,运用PCNA抗体及免疫组化过氧化物酶法 ,对受力兔前牙根尖牙周韧带细胞的增殖能力进行观察和分析。结果　正畸力作用牙齿一段时间以后 ,牙周韧带细胞增殖能力逐渐增强。结论　正畸作用力能影响牙周韧带细胞的增殖能力 。Objective To study the event of PDL cell proliferation which was induced by orthodontic forces for the experimental duration. Method[WT5”BZ] The orthodontic appliances were secured in rabbits’ mouth applied 50g of force to the teeth. The time of animal death was 1,3,7and 14d following initiation of orthodontic force. The anterior teeth and periodontal tissues were made into histological samples. To reveal the proliferating cells, paraffin sections were immunostained with PCNA antibody by the use of an indirect immunoperxidase method. Result[WT5”BZ] The results of this study indicated that the ability of PDL cell proliferation increased consistently as the experimental period prolonged.

关 键 词：正畸牙移动 细胞增殖 PCNA 正畸骨改建 牙周韧带 增殖细胞核抗原 

分 类 号：R783.5[医药卫生—口腔医学]