幽门弯曲菌与胃炎的超微结构观察  

ULTRASTRUCTURALSTUDY OF CAMPYL0BACTERPYL0RIDIS ANO GASTRITIS

作　　者：姜鉴澈 朱其栋 邹国祥[3] 谭金山[3] 侯颖一[3] 刘维勤[2] 

机构地区：[1]青岛医学院病理解剖学教研室 [2]青岛医学院附属医院内科 [3]青岛医学院电镜研究室

出　　处：《青岛医学院学报》1991年第3期234-236,6,共4页Acta Academiae Medicinae Qingdao Universitatis

摘　　要：用透射电镜对5例常规胃粘膜活检标本进行观察。5例皆为男性,年龄28～55岁,均有“胃病”史。结果发现,5例中4例有数量不等的幽门弯曲菌(CP),CP多位于上皮细胞表面、胃小凹、腺管腔及上皮细胞间沟内。上皮细胞微绒毛断裂、减少或消失;有的上皮细胞局部呈“杯状”下陷;有的向表面略突起,细胞表面呈“垫板”状增厚;有的可见与细菌之间有糖萼样细丝相连。提示CP的致病机理可能与其运动的机械作用、毒素的化学作用及其他间接作用等综合作用有关。An electron microscopic study of gastric mucosal biopsies from 5 dyspeptic patients is reported. The role of campylobacter pyloridis (CP) in the pathogenesis of gastritis is analysed. CP were found in 4 cases. Most of the CP were located on the surface of the superficial epitheliums, the pits, the gland lumens and the intercellular grooves of gastric epithelial cells. The changes found in the epithelial cells were fragmentation, decrease in number or total disappearance of the mi- crovilli. In some cases, the epithelial cells were found to have become cup-shaped or protruding in the lumen surface, or be connected to CP by sugar-coated filaments, The role of CP in the pathogenesis of gastritis was possibly the result of its drill act and toxical effect combined with other factors.

关 键 词：幽门 胃炎 病理学 

分 类 号：R573.3[医药卫生—消化系统]