红细胞免疫黏附功能和血液流变学特性与脑血管病的相关性  

Relativity Study of Red Blood Cell Immune Function, Hemorrheology and Cerebrovascular Disease

作　　者：何庭宇[1] 杜宜[2] 何洁冰[1] 梁锦胜[1] 

机构地区：[1]中山市人民医院肿瘤研究所,中山528403 [2]中山市人民医院神经内科,中山528403

出　　处：《复旦学报（医学版）》2001年第5期400-402,共3页Fudan University Journal of Medical Sciences

摘　　要：目的　探讨红细胞免疫黏附功能 (RCIA)和血液流变学特性在脑血管病发病中的临床意义。方法　对5 8例脑血栓病、5 6例高血压脑病、40例脑出血急性期 (发病 1～ 3d)患者及 6 0例健康人的RCIA功能和血液流变学多项指标的改变进行分析。结果　 3组病人与对照组比较RBC C3bRR明显下降 ,RBC ICR明显升高。血液流变学检查呈高凝血症和 (或 )红细胞聚集症。全血黏度及血浆黏度与RBC ICR相关分析呈正相关。结论　脑血管病急性期存在着RCIA紊乱 。Purpose To study clinical significance of red blood cell immune adherence function and he morrheology in cerebrovascular disease. Methods Red blood cell immune adherence function and hemorrheology index of 58 cases cerebral thrombus,56 cases hypertensive encephalopathy,40 cases cerebral hemorrhage(1-3 days of a disease) and 60 cases healthy persons were analysed. Results Three groups patients compared with control group,red blood cell C3b receptor rosette decrease significantly,red blood cell immune complex rosette increase significantly,hemorrheology test indicated hypercoagulable syndrome and/or erythrocyte aggregation,whole blood viscosity and plasma viscosity shown direct ration with red blood cell immune complex rosette. Conclusions Patients with cerebrovascular disease existed confusion of red blood cell immune function,may be related to hemorrheology abnormality.

关 键 词：脑血管病 红细胞免疫黏附功能 血液流变学 RCIA 

分 类 号：R743[医药卫生—神经病学与精神病学]