消炎利胆片中脱水穿心莲内酯的含量及含量均匀度测定  

Determination of Content and Uniformity of Dosage Units of Dehydroandrographolide in Xiaoyanlidan Tablets by HPLC

作　　者：翁雪萍[1] 李惠敏[1] 

机构地区：[1]惠州市药品检验所,广东惠州516008

出　　处：《中成药》2001年第10期717-719,共3页Chinese Traditional Patent Medicine

摘　　要：目的 :建立高效液相色谱法测定消炎利胆片中脱水穿心莲内酯的含量及含量均匀度。方法 :采用ODS柱 ,以甲醇 水 ( 70∶3 0 )为流动相 ,检测波长 2 5 0nm。结果 :脱水穿心莲内酯线性范围为 2 .14～ 3 4 .2 4 μg/mL(r =0 .9999) ,平均回收率为 99.91% ,RSD为 1.78%。结论 :本法简便、准确。Objective: To develop a HPLC method for the content and uniformity of dosage units of dehydroandrographolide in Xiaoyanlidan Tablets. Methods: ODS column was used and methanol water (70∶30) was used as a mobile phase. The detection wavelength was set at 250nm. Results: The linear range was from 2.14 to 34.24μg/mL (r =0.9999). The average recovery was 99.91%, and the relative standard deviation was 1.78%. Conclusion: The method is convenient and accurate.

关 键 词：胶水穿心莲内酯 消炎利胆片 高效液相色谱法 含量 含量均匀度 中药 

分 类 号：R286.0[医药卫生—中药学]