含氮两亲膦配体N,N′-双(二苯膦甲基)哌嗪及钯配合物的合成和催化羰化反应  

Synthesis of an Amphiphilic Phosphine Ligand N,N-bis(Diphenyl-phosphinomethyl)piperazine and its Palladium Complexes and their Catalytic Carbonylation of Benzyl Chloride

作　　者：傅相锴[1] 马学兵[1] 李龙芹[1] 陈静蓉[1] 

机构地区：[1]西南师范大学应用化学研究所,重庆北碚400715

出　　处：《分子催化》2001年第6期444-446,共3页Journal of Molecular Catalysis(China)

基　　金：重庆市科委资助课题

摘　　要：在温和的条件下 ,以季　盐 [Ph2 P(CH2 OH) 2 ]+ Cl- 与胺的曼尼希反应 ,高产率合成了含 Ph2 PCH2 N=配位基团的两亲膦配体 N,N′-双 (二苯膦甲基 )哌嗪 .在正丁醇中于氮气保护下制备了 Ph2 P/Pd摩尔比为 2∶ 1和 1∶1的钯配合物 .该钯配合物对氯苄的常压羰基化反应有很高的催化活性 ,苯乙酸的产率可达 91%A novel amphiphilic phosphine ligand N,N\|bis(Diphenylphosphinomethyl)piperazine was synthesized by reaction of piperazine with [Ph\-2P(CH\-2OH)\-2] +Cl\+- in a medium of pH 9 to 10 at 65~70 ℃ for 2.5 h with a 97% yield, and was characterized by NMR and MS. Its palladium complexes with 2∶1 or \{1∶1\} Ph\-2P to Pd molar ratios were also prepared in n\|butanol. The palladium complexes exhibit high catalytic carbonylation activities for benzyl chloride, and the catalysts can be reused.

关 键 词：含氮两亲膦配体 N N'-双(二苯膦甲基)哌嗪 合成 钯配合物 羰基化反应 催化剂 氯苄 催化活性 

分 类 号：O625.21[理学—有机化学] O643.36[理学—化学]