曲马多的临床镇痛作用观察  

Clinical function of easing pain of tramadol

作　　者：张卫芳[1] 洪海滨[2] 

机构地区：[1]惠州卫生学校,广东惠州市516020 [2]惠州市人民医院

出　　处：《井冈山医专学报》2001年第4期9-10,共2页Journal of Jinggangshan Medical College

摘　　要：目的对曲马多治疗慢性疼痛进行临床观察与评估。方法39例中度或以上慢性疼痛患者服用曲马多,观察4周后用视觉模拟评分VAS法进行疼痛评估。结果39例疼痛患者经曲马多治疗后完全缓解为20例,明显缓解为12例;中度缓解为4例;轻度缓解为2例,未缓解为1例。结论曲马多具有阿片受体的激动作用和间接调节中枢单胺类神经递质,加强疼痛下行抑制通路在内的双重作用机制,对慢性疼痛治疗具有良好的疗效。Objective：The observation and evaluatio n on tr amadol treatment of chronic pain．Method：Asking ３９chronic pain cases of mediate degree or above to have tramadol．After ４weeks observation，use VAS to evaluate the pain，Result：２０cases are completely relieved；１２cases relie ves greatly；４cases belongs to media te relief and ２cases are mild relief a f ter taking tramadol among the ３９cases，there is one case h aving no relief．Co nclusion：Tramadol has the effect of receivers stimulation and indirect adjustin g nerve centre；It also has t he effect of making the pain go down to restrain t he way；It has the good effe ct to cure chronic pain，too．

关 键 词：曲马多 镇痛 临床应用 中枢神经系统抑制药 非成瘾类镇痛药 

分 类 号：R971.1[医药卫生—药品]