银耳多糖及其衍生物抑制牛免疫缺陷病毒的实验研究  

Experimental Study of Polysaccharide from Tyemella faciformis Berk and its Sulfated Derivatives in relation with Inhibi-fion of Bovine Immunodeficiency Virus

作　　者：徐文清[1] 李美佳[1] 陈木天 

机构地区：[1]中国医学科学院中国协和医科大学放射医学研究所,天津市300192 [2]北京紫辰轩医药公司

出　　处：《中国性病艾滋病防治》2001年第5期277-278,共2页Chinese Journal of Std & Aids Prevention and Control

摘　　要：目的 寻找新的治疗艾滋病的药物。方法 用牛免疫缺陷病毒筛选抗艾滋病药物的实验模型。结果 银耳多糖及其硫酸酯在 0.2mg/ml时具有抑制牛免疫缺陷病毒引起的合胞体的作用。结论 银耳多糖及其硫酸酯可作为艾滋病高危人群的预防用药及联合其它药物用于艾滋病患者的治疗。Objective To screen new anti-AIDS drugs. Methods To screen anti - AIDS drugs using an experimen-(al model with Bovine Immunodeficiency Virus(BIV). Results Polysaccharide from Tyemella faciformis Berk and its sulfi-ated ester inhibited the syncytium formation induced by Bovine Immunodefciency Virus at 0.2mg/ml. Conclusion Polysaccharide from Tremella faciformis Berk and its sulfated ester may be used as preventive drugs for high risk groups of population for HIV/AIDS and also as curative drugs for AIDS by combining with other agents.

关 键 词：银耳多糖 牛免疫缺陷病毒 合胞体 

分 类 号：R512.910.1[医药卫生—内科学] R373.9[医药卫生—临床医学]