颞骨恶性肿瘤的分组治疗及其远期疗效观察  

Long Term Outcome of Temporal Bone Malignancies Treated According to a New Grouping Method

作　　者：曾宗渊[1] 彭汉伟[1] 许光普[1] 陈福进[1] 魏茂文[1] 伍国号[1] 郭朱明[1] 

机构地区：[1]中山医科大学肿瘤防治中心头颈科,广州广东510060

出　　处：《癌症》2001年第11期1279-1281,共3页Chinese Journal of Cancer

摘　　要：目的:评价颞骨恶性肿瘤不同分组治疗的远期疗效,探讨颞骨恶性肿瘤的合理分组方法和治疗策略。方法:回顾性分析69例颞骨恶性肿瘤治疗的远期疗效。按照病变范围将病例分成4组,按临床情况和需要给予单纯手术、单纯放疗或综合治疗,用Kaplan-Meier法计算各组生存率,并比较其生存曲线的差异。结果:全组69例患者总的5年生存率为55.2%,其中Ⅰ组84.82%,Ⅱ组57.14%,Ⅲ组29.33%,Ⅳ组8.23%,各组间生存状况有统计学差异。单纯手术组5年生存率为69.32%,单纯放疗组为51.02%,综合治疗组为54.69%,各组间的生存状况无显著性统计学差异。结论:各组的生存率曲线不相交不重叠且具有统计学意义,该分组方法对治疗方案的选择和预后的估计有一定的指导意义;对III、IV组病例应行以放射治疗为主的综合治疗。Objectives: To evaluate the long term outcome of the patients with temporal bone malignancies who were treated according to a new grouping method, and to discuss the rational classification and treatment for them. Methods: Retrospectively analyzed the long term outcome of 69 patients with temporal bone malignancies, which were divided into 4 groups according to the extent of the lesions and treated with surgery, radiotherapy, and multidisciplinary therapy. Kaplan Meier method was used to evaluate their long term survival rates. Results: 5 year survival rate of the total cases was 55.12%. 5 year survival rate of group Ⅰ was 84.82%, 57.17% of group Ⅱ, 29.3% of group Ⅲ, and 8.23% of group Ⅳ respectively, the difference among which was statistically significant. The 5 year survival rate of the cases treated only by surgery was 69.32%, by radiation 51.02% and by multidisciplinary therapy 54.69%, there was no statistic significance. Conclusions: The methods of grouping mentioned above are useful in clinics when therapeutic methods and prognosis were considered, the survival curves of each group of which go without overlap or crossover. Group III and IV should be treated mainly by radiotherapy.

关 键 词：颞骨肿瘤 治疗 长期疗效 

分 类 号：R739.8[医药卫生—肿瘤]