四肢恶性骨肿瘤保肢术前化疗栓塞的初步应用  

Preliminary Study of Transcatheter Arterial Chemoembolization for MalignantLimb Bone Tumor Before Limb-sparing Operation

作　　者：梅雀林[1] 李彦豪[1] 鲁恩洁[1] 

机构地区：[1]第一军医大学南方医院放射科,广东广州510515

出　　处：《实用放射学杂志》2001年第10期751-753,共3页Journal of Practical Radiology

摘　　要：目的　探讨四肢恶性骨肿瘤术前化疗栓塞价值及其对手术治疗的影响。方法　对 10例恶性骨肿瘤患者保肢手术前行超选择插管化疗栓塞 ,并对栓塞后并发症、肿瘤大体标本及组织学切片、手术切口愈合情况进行观察。结果　全部患者均有明显的栓塞后综合征 (患肢明显肿胀、剧痛等 ) ,2周后消失或明显减轻。局部皮肤坏死 1例。栓塞后 6 2 8d ,瘤体呈不同程度的凝固性坏死 ,其中坏死达 6 0 %以上者 8例 ;术后切口全部Ⅰ期愈合。结论　化疗栓塞术是四肢恶性骨肿瘤保肢术前的一种有效。Objective To evaluate the values of transcatheter arterial chemoembolization(TACE)for malignant limbs bone tumors before limb-sparing operation and the influence of TACE on operation.Methods TACE was performed in 10 patients with malignant limb bone tumor before limb-sparing operation.The complication of TACE,morphology and histology of neoplasm,incisional healing after TACE were observed.Results (1)The embolization syndrome (swelling,pain)appeared obviously in all patients at early stage and disppeared or alleviated greatly after 2 weeks of TACE.The severe complication-local skin necrosis appeared in 1 case;there was a subcrustal healing after 3 weeks.(2)In 6~28 days after embolization,all neoplasms underwent coagulation to variable extents,and the tumor cells was more than 60% necrosis in 8 cases.(3)All incisions had a good healing by first intention.Conclusion TACE is an effective and safe accessory therapeutic preecdure for malignant limbs bone tumors before limb-sparing operation.

关 键 词：治疗性栓塞 保肢手术 骨肿瘤 肿瘤 

分 类 号：R738.1[医药卫生—肿瘤] R739.96[医药卫生—临床医学]