稀释式自体输血与血液稀释用于乳腺癌根治术的临床观察  

Clinical study on dilute autotransfusion and acute hemodilution in patients with breast cancer during radical operation

作　　者：林鹰[1] 赵海芳[1] 李伟[1] 杨光[1] 郑丽宏[1] 

机构地区：[1]哈尔滨医科大学附属第三医院麻醉科,黑龙江哈尔滨150040

出　　处：《哈尔滨医科大学学报》2001年第6期448-450,共3页Journal of Harbin Medical University

摘　　要：目的　观察在乳腺癌根治术中采用稀释式自体输血和急性血液稀释对血液生理的影响。方法　 2 4例乳腺癌根治术病人ASAⅠ～Ⅱ级 ,随机分为自体输血组 (AT)和血液稀释组 (HD)。全麻下 ,AT组采血 396～ 6 39ml,并输等量 6 %羟乙基淀粉 (HES)注射液 ,HD组先输入HES 5 0 0ml后手术。监测术中失血量、输液量、循环生理指标 ,检验术前 (T1)、血液稀释后输自体血前 (T2 )及术后 1日 (T3)的Hb、RBC、Hct、Plt、WBC。结果　AT组T2 的Hb、RBC、Hct值明显低于HD组 (P <0 .0 5 ) ,而T3 明显高于HD组 (P <0 .0 5 )。结论　稀释式自体输血能更有效地减少血液流失 。Objective To observe the influence of dilute autotransfusion and acute hemodilution on hematophysiologic function in patients with breast cancer during radical operation.Methods Tenty four patients with breast cancer,ASA Ⅰ～Ⅱ,were randomly divided into two groups:autotransfusion(AT) group and hemodilution(HD) group.396～639ml blood was collected after general anesthesia and the same amount of 6% HES was infused before operation in AT group;500ml HES was injected;before operation in HD group.Blood loss volume,amount of fluid and cyclic physiologic index were monitored during operation.The Hb,RBC,Hct,Plt and WBC were measured and recorded at following occasions:before operation (T 1),after hemodilution or before autotransfusion (T 2) and one day after operation (T 3).Results Compared with HD group,Hb,RBC and Hct decreased significantly at T 2 ( P <0.05),but incresased significantly at T 3 ( P <0.05) in AT group.Conclusion Effect of dilute autotransfusion is better than hemodilution in minizing blood loss and preserving RBC.

关 键 词：乳腺癌 自体输血 血液稀释 

分 类 号：R737.9[医药卫生—肿瘤]