脑膜癌病临床与脑脊液细胞学研究  

Meninges carcinoma and cytologic examination of cerebrospinal fluid (CSF)

作　　者：陈慧敏[1] 吴延林[1] 何向蕾[1] 

机构地区：[1]宁波市医疗中心李惠利医院,315041

出　　处：《浙江临床医学》2001年第6期387-388,共2页Zhejiang Clinical Medical Journal

摘　　要：目的 探讨脑膜癌病的临床特征和脑脊液细胞学改变。 方法 总结分析11例经脑脊液细胞学检查确诊的脑膜癌病患者的临床资料。结果 临床上以颅内高压、脑膜刺激征阳性和颅神经损害为主要表现 ,头颅CT、MRI检查常为阴性 ,脑脊液细胞学检查肿瘤细胞检出率高 ,细胞免疫组化染色对鉴定肿瘤细胞性质有帮助。 结论 脑脊液细胞学检查结合细胞免疫组化染色是诊断脑膜癌病最佳手段。Objective To explore clinical features of meninges carcinoma and cytologic changes of CSF. Methods The clinical data of 11 cases meninges carcinoma that were diagnosed by cytologic examination of CSF were analyzed. Results The main clinical features were intracranial hypertension, meningeal stimulating sign and injury of cranial nerves. CT and MRI examination often could not find the lesions, but there was high positive rate in cytologic examination of CSF, and immunohistochemistry helped to determine the characteristics of lesions. Conclusion Combined with immunohistochemistry, cytologic examination of CSF was an ideal method to diagnose meninges carcinoma.

关 键 词：脑膜癌病 脑脊液细胞学 免疫组化染色 

分 类 号：R739.45[医药卫生—肿瘤]