癌细胞分化诱导剂多亚甲基二甲酰胺噻唑啉衍生物的合成  

STUDY ON INDUCERS OF DIFFERENTIATION OF CARCINOMA CELLS:SYNTHESIS OF POLYMETHYLENEDICARBOXAMIDE THIAZOLINE DERIVATIVES

作　　者：文晓霞[1] 王慧才[1] 

机构地区：[1]山东医科大学有机化学教研室

出　　处：《山东医科大学学报》1991年第2期165-168,共4页Acta Academiae Medicinae Shandong

摘　　要：根据极性平面化合物的构效关系,设计合成了4个多亚甲基二甲酰胺噻唑啉衍生物,其结构由元素分析、红外吸收光谱和核磁共振谱证实。In an attempt to discover a more potent inducer of differentia- tion,the structure-activity relationship of polar-planar inducers was studied and four polymethylenedicarboxamide thiazoline derivatives were synthesized. Their chemical structures were confirmed by elementary analysis,IR and NMR spectra.

关 键 词：分化诱导剂 噻唑啉衍生物 合成 

分 类 号：TQ463.53[化学工程—制药化工]