组织蛋白酶-D的生物学特性及其与乳腺癌预后的关系  

THE BIOLOGICAL CHARACTER OF CATHEPSIN-D AND ITS PROGNOSIS VALUE IN BREAST CANCER

作　　者：王睿敏[1] 王睿君[2] 马激扬[1] 

机构地区：[1]内蒙古医学院第一附属医院保健病房,内蒙古呼和浩特010050 [2]内蒙古医学院

出　　处：《内蒙古医学院学报》2001年第4期277-280,共4页Acta Academiae Medicinae Neimongol

摘　　要：查阅了国内、外 1979～ 1999年的有关文献。对有关Cath -D乳腺癌病人的预后有如下观点 :a .Cath-D能促进乳腺癌的转移、扩散 ,Cath -D阳性染色或高表达与不良预后有关。b .Cath -D属于雌激素调控蛋白家族 ,与乳腺癌好的预后相关。Cath -D是否能够促进乳腺癌的转移和扩散 ,仍有分岐 ,但多数学者趋向于肯定的结论。Looking about the documents concerned at home and abroad from 1979 to 1999,there are two kinds of view,about the prognosis of breast cancer patient by Cath-D:a:Cath-D can stimulate the breast cancer metastasis, invasion, the positive expresson of Cath-D or high expression was correlated wih the bad prognosis. b: Cath-D was belong to the estrogen-regulated protein family, and related to the good prognosis. There are different kinds of view about the relation between the Cath-D and the prognosis of breast cancer. But the most scholars are inclined to the view that the positive expression of Cath-D was correlated with bad prognosis of breast cancer.

关 键 词：组织蛋白酶 乳腺癌 细胞生物学 预后 

分 类 号：R737.902[医药卫生—肿瘤]