清血降脂胶囊的制备工艺研究  

Studies on processes for preparation of QINGXUE JIANGZHI CAPSULE

作　　者：冯淑华[1] 周晶[1] 乔卫[1] 符敬伟[1] 张晓梅[1] 

机构地区：[1]天津医科大学,天津300203

出　　处：《中草药》2001年第9期793-794,共2页Chinese Traditional and Herbal Drugs

摘　　要：目的　研究清血降脂胶囊的制备工艺。方法　采用均匀设计方法 ,以总有机酸、总多糖为指标 ,对制备胶囊浸膏的提取溶剂比、煎煮时间、醇沉浓度等关键工艺步骤进行考查。结果　该制剂的最佳工艺条件为 :药材与溶剂比为 1∶ 10 ,煎煮 2次 ,每次为 6 0 min,醇沉浓度为 5 0 %。结论　以本工艺条件提取有效成分 ,不仅保证有机酸的含量 ,同时也使多糖不受损失。Object To establish a process for the preparation of QINGXUE JIANGZHI CAPSULE(Hemocathartic Antilipemia Capsule)  Methods The study was carried out by uniform experimental design guided by the content of total organic acid and polysaccharide in the resulting preparation, to optimize the ratio of solvents used for the extraction, time needed for the decoction and alcoholic concentration for precipitation Results The most favorable preparative conditions were: decocting the drug twice with 10 times of water for 60 min each time, and precipitate the product at a concentration of 50% alcohol Conclusion Products prepared by this process ensured the content of total organic acid with no loss of polysaccharides

关 键 词：清血降脂胶囊 均匀设计 制备工艺 有机酸 多糖 中药 

分 类 号：TQ461[化学工程—制药化工] R286.0[医药卫生—中药学]