氯化钠溶液对人牙根面牙本质早期龋再矿化作用的影响  

Effect of sodium chloride treatment on remineralization of human root dentine caries in vitro

作　　者：王晓灵[1] 王勤[1] 

机构地区：[1]北京大学口腔医学院防龋研究室,100081

出　　处：《中华口腔医学杂志》2002年第1期30-32,T007,共4页Chinese Journal of Stomatology

摘　　要：目的　探讨单纯用氯化钠 (NaCl)溶液处理人牙根面牙本质早期龋后 ,提高根面早期龋再矿化作用的可行性。方法　在人牙根面上形成早期人工龋 ,将标本分组 ,分别用 0 5mol/LNaCl溶液和 0 5mol/LEDTA二钠盐溶液浸泡后 ,用再矿化液处理。扫描电镜下观察比较早期龋矿化前牙根表面形态及矿化后牙根表面矿物盐沉积情况 ;显微X线照像及其图像分析比较矿化后矿物含量的不同。结果　人牙根面早期龋表面用NaCl溶液浸泡前后无明显改变 ;早期龋用EDTA二钠盐溶液浸泡后表面见大量牙本质小管开放。再矿化后 ,前者比后者表层明显增厚 ,表层阻射度明显增强。结论　用NaCl溶液处理人牙根面早期龋以后 ,再矿化效果明显增强 ,NaCl溶液对早期龋表面无不良影响。Objective To investigate the influence of soluble phosphoprotein removal from artificial dentin caries lesions by pretreatment of NaCl on subsequent remineralization Methods Human root dentin samples were demineralized in an acidic gel(pH=4 4)at 37℃ for 48 hours Samples were pretreated with 0 5 mol/L NaCl solution and 0 5mol/L disodium EDTA solution respectively The histomorphologic changes of root caries surface were examined by scannings electronic microscope Mineral profiles were assessed by means of microradiography. Results No histomorphologic changes were present on root caries surface after treated with 0 5 mol/L NaCl solution , while many opened dentin tubules were seen after treated with 0 5 mol/L disodium EDTA solution The remineralization results showed that pretreatment with 0 5 mol/L NaCl solution increased more remineralization than pretreated with 0 5 mol/L disodium EDTA solution Conclusion 0 5 mol/L NaCl solution has no damage on the root caries surface The in vitro results suggested that removal of soluble phosphoprotein from dentin lesions is an intresting approch to enhance remineralization

关 键 词：龋齿 磷蛋白类 氯化钠 牙再矿化 

分 类 号：R781.1[医药卫生—口腔医学]