金因肽对过敏性口炎的临床疗效观察  

Observing the clinical effect of rhEGF solution for treating allergic stomatitis

作　　者：张水龙[1] 周曾同[1] 许国祺[1] 

机构地区：[1]上海第二医科大学附属第九人民医院口腔内科,上海200011

出　　处：《临床口腔医学杂志》2002年第1期53-54,共2页Journal of Clinical Stomatology

摘　　要：目的　观察金因肽对过敏性口炎的临床疗效。方法　选择 2 0例过敏性口炎患者 ,随机分成两组 ,治疗组用金因肽溶液喷洒损害区 ,对照组喷洒安慰剂 ,将疗效进行对比研究。结果　治疗组平均愈合时间为 3d ,而对照组为 5 .5d ,治疗组的有效率 (60 % )显著高于对照组 (10 % ) (P <0 .0 5 ) ,治疗组的总有效率 (10 0 % )亦显著高于对照组 (60 % ) (P <0 .0 5 )。结论　金因肽能快速促进过敏性口炎。Objective To observe the clinical effect of recombinant human Epidermal Growth Factor(RHEGF) for treating allergic stomatitis. Methods Twenty cases of allergic stomatitis were chosen and divided into two groups randomly. rhEGF solution was sprayed on the erosive areas of the treatment group, nevertheless, placebo sprayed on the ones of the control group. And then compared the results. Results The average curing time of the treatment group was 3 days, but that of the control group was 5.5 days. The excellent rate of the treatment group(60%) was significantly higher than that of control group(10%)( P < 0.05 ); the total effective rate of the treatment group(100%) was also higher than that of control group(60%)( P < 0.05 ).Conclusion RHEGF can accelerate the curing time of oral erosion and ulcer. Therefore, it is highly recommended and popularized.

关 键 词：金因肽 过敏性口炎 治疗 疗效 

分 类 号：R781.5[医药卫生—口腔医学] R969.4[医药卫生—临床医学]