老年牙周炎患者牙龈组织NO水平研究  

A study of NO level in gingival tissue of elderly patients with periodontitis

作　　者：毛钊[1] 杨俭[2] 曹永安[2] 吴织芬[1,2] 

机构地区：[1]西安第四军医大学口腔医学院 [2]江苏职工医科大学

出　　处：《实用口腔医学杂志》2001年第5期397-399,共3页Journal of Practical Stomatology

摘　　要：目的 :观察老年牙周炎患者牙龈组织中 NO水平变化并与健康老年人、慢性成人牙周炎患者、青少年牙周炎患者比较。方法 :采用硝酸还原酶法测量老年牙周炎患者、健康老年人、慢性成人牙周炎患者和青少年牙周炎患者牙龈组织中 NO含量并比较。结果 :老年牙周炎组 NO水平明显低于健康老年人组、慢性成人牙周炎组和青少年牙周炎组 ( P<0 .0 5 )。结论 :由于衰老和牙周炎症的双重作用 ,老年牙周炎患者牙龈组织生成和分泌 NO明显减少 ,导致抗感染和免疫调节功能的改变 ,非特异性免疫功能降低。砄bjective: To observe NO level in gingival tissue of elderly patients with periodontitis. Methods: 4 mm 3 gingival tissue was obtained during tooth extraction and NO in the tissue of 14 patients aged 65～81 years with periodontitis was measured with nitrate reductase assay. The NO level was compared with that of 9 adult patients (40～58 years old), 6 juveniles patients (25～30 years old) with periodontitis and 9 health elders(65～77 years old).Results:NO(μmol/L)in gingival tissue of elderly patients,health elders,adult patients and juvenile patients were 33.07±12.02,63.53±18.23,55.99±22.40 and 82.15±30.35 respectively.( P <0.05).Conclusion:Aging and inflammation may result in decrease of the production of NO in elderly patients with periodontitis.

关 键 词：老年人 牙周炎 一氧化氮 NO 

分 类 号：R781.42[医药卫生—口腔医学]