恶性肿瘤与血清唾液酸水平相关性研究  

Interrelated study on cancer and sialic acid level in serum

作　　者：王玉兰[1] 赵卫军[1] 谷静丽[1] 

机构地区：[1]河南大学医学院生化教研室,河南开封475001

出　　处：《河南大学学报（医学科学版）》2001年第2期14-15,共2页

摘　　要：目的 :研究血清唾液酸水平与恶性肿瘤的关系 ,探讨恶性肿瘤的早期诊断方法。方法 :对 80例正常人和12 0例恶性肿瘤患者的血清采用快速比色法 ,在国产 72 2型分光光度计上进行唾液酸的检测分析。结果 :正常组与各类恶性肿瘤组有显著差异。正常人阳性率为 0 %肺癌组阳性率 92 .5 %、肝癌组阳率 88.5 %、胃癌组阳性率 90 %、食道癌组阳性率 89.4%、乳腺癌组阳性率 75 %、卵巢癌组织阳性率 75 %。结论 :恶性肿瘤患者血清唾液酸水平升高。血清唾液酸对恶性肿瘤有诊断价值。Objective To study the relationship of sialic acid level in serum and cancer, and to probe into the early diagnostic methods of cancer. Methods The sialic acid of blood serum of 80 healthy persons and 120 cases of cancers were determined and analysed by rapid colorimetric method, with home_made spectrometer Model 722. Results The contrast group differs greatly from all kinds of cancer groups. The positive rate of healthy person group is 0%, that of lung cancer group 92.5%, that of liver cancer group 88.5%, that of stomach cancer group 90%, that of esophagus cancer group 89.4%, that of breast cancer group 75%, and that of ovary cancer group 75%. Conclusion Cancer patients sialic acid level of blood serum increase. So sialic acid has diognostic value to cancer.

关 键 词：血清唾液酸 恶性肿瘤 诊断 

分 类 号：R730.4[医药卫生—肿瘤] R730.2[医药卫生—临床医学]