石墨和磷酸盐包埋料对纯钛铸件生物学性能的影响  

Effect of Graphite and Phosphate Investments on the Biological Characteristics of Pure Titanium Castings

作　　者：阎俏梅[1] 张建中[1] 

机构地区：[1]上海第二医科大学附属第九人民医院口腔医学院口腔修复科,上海200011

出　　处：《上海口腔医学》2001年第4期349-352,共4页Shanghai Journal of Stomatology

摘　　要：目的　了解石墨及磷酸盐包埋料所致纯钛铸件表面结构的改变对纯钛铸件生物学性能的影响。方法　用石墨和磷酸盐包埋料铸造加工圆片状铸件若干 ,以相同规格的牙胶为对照 ,分打磨抛光前后共 4组进行细胞毒性试验、粘膜刺激试验。结果　根据国际标准化组织ISO文件和我国医用生物材料性能测试标准 ,4组试件的细胞毒性试验均为I级。病理反应分级均为 0级。结论　两种包埋料所致纯钛铸件表面结构的变化未导致其生物学性能方面的明显改变。Objective To investigate the effect of surface structural changes caused by graphite and phosphate investments on the biological characteristics of pure titanium castings.Methods Round casting pads of pure titanium were processed by graphite and phosphate investments respectively, then grouped into four. With the control of guta purca of the same size, Ultraviolet spectrometry was used to test the cytotoxicity of samples via the ISO, GB and Shanghai biomaterial research and testing center's standards. Mucous irritation test was performed on hamsters' pouch.Results Titanium castings obtained from both investment materials have reached the national standard of cytotoxicity and mucous irritation test no matter they have been undergone surface treatment or not.Conclusion Both investment materials cause no obvious changes on biological characteristics of pure titanium castings with the existing of surface structural changes.

关 键 词：石墨 磷酸盐 表面反应 细胞毒性 粘膜刺激试验 牙科种植体 纯钛铸件 生物学性能 

分 类 号：R783.1[医药卫生—口腔医学]