MEA方案治疗成人急非淋白血病的疗效分析  

Analysis of effectiveness of MEA REgimens on adult ANLL

作　　者：黎爱华[1] 李秀兰[1] 滕清良[1] 李欣[1] 潘浩[1] 朱艳清[1] 

机构地区：[1]泰安市中心医院血液内科,山东泰安271000

出　　处：《临床血液学杂志》2001年第6期258-259,共2页Journal of Clinical Hematology

摘　　要：目的 :观察MEA方案在HA或DA化疗未达CR的ANLL(M4 、M5)患者的治疗效果 ,并与传统治疗方案进行比较。方法 :对诊断明确者随机分为MEA治疗组和DA或HA治疗组 ,MEA组 1疗程后 ,DA或HA组2个疗程后评价疗效。结果 :MEA组CR率为 76 .5 % ,总有效率 88.2 % ,DA或HA组一疗程后CR率分别为33.3%、30 % ,总有效率都为 6 0 %。两组相比MEA方案的骨髓抑制作用强于DA/HA组 ,而非造血系统不良反应差异无显著性。结论 :MEA方案对ANLL(M4 、M5)的疗效显著优于DA、HA方案 ,可考虑作为ANLL(M4 、M5)Objective: To observe the effect of MEA in the cases of ANLL who didn′t obtain CR after the treatment of HA or DA and who were ANLL-M 4 or ANLL-M 5.Method: The patients randomly separated into two groups.One was treated with MEA,the other with DA or HA.The effects of the two groups were compared after MEA was treated one time and DA or HA was treated two times.Result: The CR rate of MEA group is 76.5 %.It is obvioulsy more than the rate of DA or HA team.Conclusion: The effect of MEA in the cases of ANLL who didn′t obtain CR after the treatment of HA or DA and who is ANLL-M 4 or ANLL-M 5 is better than that of DA and HA group.

关 键 词：急性非淋巴细胞性白血病 诱导化疗 疗效 MEA方案 

分 类 号：R733.71[医药卫生—肿瘤]