脂肪肝与高脂血症关系的实验研究  

Experimental Study of the Correlation Between Fatty Liver and Hyperlipemia

作　　者：李靖环[1] 弓青梅[2] 杨栓平[3] 王志平[3] 郝一彬[3] 

机构地区：[1]山西职工医学院,030012 [2]山西煤炭中心医院 [3]山西医科大学

出　　处：《长治医学院学报》2001年第4期241-243,共3页Journal of Changzhi Medical College

摘　　要：目的 :探讨脂肪肝与高脂血症之间的关系。方法 :将实验动物随机分为两组 ,对照组采用基础饮食 ,实验组采用高脂饮食 (基础饮食基础上加 1 %胆固醇 ,5 %猪油 ,1 0 %玉米油 ) ,分别饲喂Wistar大鼠三个月后 ,取血、肝标本 ,进行生化检测和病理组织学检查。结果 :①血脂和肝内脂质变化 ,与对照组相比 ,实验组大鼠血TG、Tch、LDL和肝内TG的含量均明显升高。②组织病理学检查 :实验组大鼠的肝脂肪变性明显。结论objective:To explore the correlation between fatty liver and hyperlipemia.Methods:20 Wistar rats were randomized 2 groups:normal control and high fat diet group.Rats were sacrificed at three months after ecperiment.Plasma lipid and hepatic triglyceride(TG) content were measured and hepatic pathological histology was observed.Results:As compared with normal control gruop,plasma TG and hepatic TG content was increased significantly and steatosis was observed in high fat diet group.Conclusions;There is close relationship between fatty liver and hyperlipemia chronically high fat diet.

关 键 词：脂肪肝 高脂血症 血脂 

分 类 号：R575.5[医药卫生—消化系统] R589.2[医药卫生—内科学]