鼠三叉神经痛脑干组织中P物质的测定  

The Survey of Substance P of Brain Stem in Rats with Trigeminal Neuralgia.

作　　者：樊英显[1] 艾永华[1] 孙宏晨[1] 

机构地区：[1]吉林大学口腔医院,吉林长春130041

出　　处：《口腔医学纵横》2002年第1期18-19,共2页Journal of Comprehensive Stomatology

摘　　要：目的 :检测鼠三叉神经痛时脑干组织中P物质含量的变化。方法 :建立鼠三叉神经痛动物模型 ,用放射免疫分析法测定脑干组织中P物质含量。结果 :实验组脑干组织中P物质含量明显高出对照组 (P <0 .0 1)。结论Measure the changes of substance P of brain stem in rats with trigeminal neuralgia.Methods:Establish the animal model with trigeminal neuralgia in rats.Measure the concentration of substance P of brain stem by radioimmunological analysis.Results:The substance P of brain stem in experimental group rats is significantly higher than the concentration of the control group tats.Conclusions:Substance P may mediate the conduction of the nociceptive signals from the trigeminal neuralgia.

关 键 词：三叉神经痛 P物质 脑干 放射免疫分析 

分 类 号：R780.2[医药卫生—口腔医学]