垂体腺瘤的X刀治疗  

Initial clinical results of stereotactic radiosurgery and stereotactic radiotherapy for pituitary ad- enomas

作　　者：闫志钧[1] 林志国[1] 沈红[1] 李庆国[1] 隋立森[1] 浦松[1] 

机构地区：[1]哈尔滨医科大学第一临床医院X刀,立体定向神经外科,150001

出　　处：《立体定向和功能性神经外科杂志》2001年第4期220-222,共3页Chinese Journal of Stereotactic and Functional Neurosurgery

摘　　要：目的：观察分析 Ｘ刀对垂体腺瘤的治疗效果。方法：对１９９７年１月至 ２０００年６月应用 Ｒａｄｉｏｎｉｃ公司头部Ｘ刀系统，治疗的垂体腺瘤患者随访５４例，单次治疗３２例，分次治疗２２例。其中 ５４例获得影象学复查，３６例获得血激素水平复查。随访期３个月到３２个月，平均１３ ２个月。结果：肿瘤缩小达５５．６％，无一例肿瘤增大；临床症状改善率７２．２％，无临床症状加重着。血激素水平恢复正常达３０．６％。结论：Ｘ刀治疗垂体腺瘤安全、有效，无明显副作用，ＳＲＴ治疗后血激素水平恢复正常率高于ＳＲＳ治疗，但血激素水平恢复时间长于ＳＲＳ治疗。Objective: To evaluate the initial results of stereotactic radiosurgery (SRS) and frac- tionated stereotactic radiotherapy(SRT) pituitary adenomas with regard to tumor and hormonal con- trol. Methods: 54 patients with pituitary adenomas who nuderwent SRS or SRT between January 1997 and June 2000 reciowere follow - up survey. Of these, 54 patients received CT of MRI reexamination. 36 patients received blood hormone reexamination. These patients were follow - up from 3 months to 32 months. Mean time was 13. 2 months. Results: The percentage of pituitary adenomas shrink was 55. 6 %. there was no tumor geowth. The remission rate of clinical sympton was 72. 2 %. The recovery rate of blood hormone was 30. 6 %. Conclusion: X - knife is valuable for treatment of pituitary adeno- mas and it is well tolerated therapy. The recovery rate of blood hormone were more effective SRT than SRS. The time of hormone rcivery were longer in SRT than SRS.

关 键 词：垂体腺瘤 X-刀 单次治疗 分次治疗 

分 类 号：R736.405[医药卫生—肿瘤]