静滴尼莫地平治疗脑出血的疗效研究  

Study of cerebral hemorrhage treated with intravenous nimodipine

作　　者：苏东升[1] 杨红 钟平[1] 

机构地区：[1]安徽宿州市立医院神经内科,宿州23400 [2]安徽宿州市立医院CT室,宿州23400

出　　处：《河南实用神经疾病杂志》2001年第6期5-7,共3页Henan Journal of Practical Nervous Diseases

摘　　要：目的 :观察尼莫地平治疗急性脑出血的临床疗效。方法 :应用前瞻性随机单盲方法 ,对 96例经CT证实为急性脑出血病人 ,在起病 4 8h内随机分为治疗组和对照组 ,治疗前后比较两组病人神经功能缺损程度积分差及颅内血肿体积 ,血肿周围水肿带面积的改变。结果 :尼莫地平治疗组较对照组血肿周围水肿带面积明显缩小 (P <0 0 5 ) ,神经功能缺损评分明显改善 (P <0 0 1) ,血肿体积则改变不明显。结论 :在脑出血急性期应用尼莫地平治疗 。Objective:To observe the clinical curative effects of acute cerebral hemorrhage treated with nimodipine.Methods:Using method of foreseeable randomization of sampling,96 cases of acute cerebral hemorrhage patients comfirmed by CT scan were divided into treatment group and control subjects during 48 hours after the onset.Before and after treatment,the integral difference of lesion degree of nerve function.Intracranial hematoma and the change of area of edema zone around hematoma were compared between the two groups.Results:The area of edema zone around hematoma of the treatment group shrunk obviously(P<0 05),the integral of lesion of nerve function changed markedly(P<0 01).Whereas the volume of hematoma changed unobviously.Conclusion:Nimodipine used in acute cerebral hemorrhage can improve obviously the patients' condition.

关 键 词：脑出血 尼莫地平 缺血性损害 脑水肿 疗效 

分 类 号：R743.340.5[医药卫生—神经病学与精神病学]