饮酒与脂肪肝发病关系及其影响因素的病例对照研究  

The Case-control Study of Relationship between Drinking and Fatty Liver in Shiyan

作　　者：李兆林[1,2] 孙秀发[3] 王建平[1] 易卫斌[1] 张勇[1] 杨刚[1] 张锐[1] 梅玉发[1] 张海燕[1] 

机构地区：[1]十堰市卫生防疫站 [2]华中科技大学同济医学院营养卫生学教研室,湖北武汉430030 [3]华中科技大学同济医学院营养卫生学教研室

出　　处：《中国慢性病预防与控制》2002年第1期23-23,共1页Chinese Journal of Prevention and Control of Chronic Diseases

摘　　要：目的评价饮酒、饮食、经济因素以及体重、血糖、血脂、肝炎病毒携带情况与脂肪肝危险性的关系。方法采用 1∶ 2配对研究方法 ,共调查十堰地区 81例经 B超诊断的脂肪肝病人及 16 2例对照者。通过 SAS(6 .12 )软件对资料进行条件 L ogistic回归分析。结果酒龄长、日均饮酒量大 (>5 0 g/ d)、体质指数高 (BMI≥ 2 5 )、年均醉酒次数多、血总胆固醇含量高与脂肪肝危险性增加有关联 (P<0 .0 5 ) ,蔬菜日均进食量与脂肪肝危险性降低有关联 (P<0 .0 5 )。结论十堰市居民脂肪肝的重要危险因素是日均饮酒量大 (>5 0 g/ d,OR:3.6 2 )、体质指数高 (BMI≥ 2 5 ,OR:1.811)、年均醉酒次数多(OR:1.5 6 )、血总胆固醇含量高 (OR:1.2 2 8)、酒龄长 (OR:1.0 6 6 )。而蔬菜日均进食量 (OR:0 .989)Objective To evaluate the relationship between fatty liver and drinking habits,food habits,economical factors,body weight,blood glucose,blood lipids,carrier of hepatitis virus.Methods Adopting the 1∶2 match method we investigated 81 fatty liver ca ses diagnosed by B ultrasonic and 162 controls,analyzed data using conditional Logistic regression with SAS (6.12) software.Results Long term drinking,mass drinking (>50 g/d),higher BMI (≥25),high frequence of intoxication in a year,high total blood cholesterol were highly correlated with the risk of fatty liver incidence ( P <0 05) and there was a negative correlation between vegetable consumption and fatty livdr incidence ( P <0.05).Conclusions In Shiyan residents,the most important risk factors of fatty liver were mass drin king (>50 g/d, OR :3.62),high BMI (≥25, OR :1.811),high frequency of intoxication ( OR :1.56),high total blood cholesterol ( OR :1 228),long term drinking ( OR :1 066),and the most important protective one was taking more vegetables ( OR :0.989)( P <0.05).

关 键 词：脂肪肝 配对病例对照研究 饮酒 条件Logistic模型 

分 类 号：R575.5[医药卫生—消化系统]