0.2%阿法根滴眼液对视网膜血流影响的研究  

Effect of Brimonidine 0.2% on retinal blood flow

作　　者：李扬[1] 余敏斌[1] 刘杏[1] 凌运兰[1] 郑小平[1] 

机构地区：[1]中山医科大学中山眼科中心,广州510060

出　　处：《眼科研究》2001年第4期353-355,共3页Chinese Ophthalmic Research

摘　　要：目的　　研究０．２％阿法根（Ｂｒｉｍｏｎｉｄｉｎｅ）滴眼液对视网膜血流的影响。方法　选取开角型青光眼或高眼压症患者 １５例，采用自身对照方法，于０．２％阿法根滴眼液治疗前和治疗后 ２ｈ分别行海德堡视网膜血流计（ＨＲＦ）检查，观察视网膜中央动脉颞上、颞下、鼻上、鼻下４条分支血管血容量、血流及血流速度的变化。结果　０．２％阿法根滴眼液治疗前后视网膜中央动脉颞上、颞下、鼻上、鼻下４条分支血管的血容量、血流及血流速度无明显改变。结论　０．２％阿法根滴眼液局部使用对视网膜血流无影响。Objective To investigate the effect of Brimonidine 0. 2% on blood flow using the Heidelberg Retina Flowmeter (HRF). Methods using auto-control method,we examined the volume, flow and velocity of the superior nasal and temporal, the inferior nasal and temporal artery of retina before and after single instillation of Brimonidine 0. 2% for 2 h. Results There are no significant changes in volume, flow and velocity of four arteries after the administration of Brimonidine 0. 2%. Conclusion There are no significant ocular haemodynamic benefits associated with Brimonidine therapy.

关 键 词：青光眼 药物治疗 视网膜血流 阿法根滴眼液 

分 类 号：R774.1[医药卫生—眼科]