肝硬化失代偿期钠代谢的变化  

Sodium metabolic change in cirrhosis patients in decompensation

作　　者：田怡[1] 吴炎[1] 

机构地区：[1]蚌埠医学院附属医院消化内科,安徽蚌埠233004

出　　处：《蚌埠医学院学报》2002年第2期112-113,共2页Journal of Bengbu Medical College

摘　　要：目的 :观察肝硬化失代偿期患者钠代谢变化的特点。方法 :对 1 2 6例肝硬化失代偿期患者进行血Na+ 检测 ,同时进行Child Pugh肝功能分级。结果 :有 46 .0 3 %的患者发生低钠血症 ,且随着肝功能分级的增高而明显 (P <0 .0 5) ;肝硬化腹水时低钠血症的发生率为 54 .35 % ;低钠血症时肝硬化的严重并发症及病死率均明显高于正常血钠组 (P <0 .0 0 5)。结论 :肝硬化失代偿期患者多数并发低钠血症 ,其发生与腹水的产生及肝功能状况有关 ;Objective:To observe the characteristics of sodium metabolic change in cirrhosis patients in decompensation.Methods:Blood Na\++ testing for 126 cirrhosis patients in decompensation was performed,meanwhile Child Pugh liver function was classified.Results:46.03% of the patients manifested hyponatremia,the higher the liver function classification,the more obvious the hyponatremia( P <0.05);When the patients had cirrhosis ascitic fluid,the occurrence rate of hyponatremia would reach 54.35%.The rate of serious complication and death for patients with cirrhosis accompanied by hyponatremia was obviously higher than for those with normal blood sodium level( P <0.005).Conclusions:Most cirrhosis patients in decompensation will suffer from hyponatremia complication,which is related to ascitic fluid and liver function.Hyponatremia is the possible reason for serious cirrhosis complication and death.

关 键 词：肝硬化 血钠过少 失代偿期 钠代谢 变化 

分 类 号：R575.2[医药卫生—消化系统]