肝癌患者HBV、HCV、HGV、TTV感染状况及其介入治疗中术者感染的预防  

The infections of HBV HCV HGV TTV in patients with hepatocellular carcinoma (HCC) and the possibility and prevention in interventional treatment.

作　　者：张文杰[1] 余新林[1] 杜彩霞[1] 印强[1] 杜绍财[2] 

机构地区：[1]兰州铁路局中心医院传染科,兰州730000 [2]北京医科大学肝病研究所,北京100044

出　　处：《陕西肿瘤医学》2002年第1期27-28,共2页ShanXi Oncology Medicine

摘　　要：目的　通过了解肝癌患者HBV、HCV、HGV、TTV感染状况 ,探讨在肝癌介入治疗术中经血源传播病原体感染的可能性及预防。方法　采用免疫PCR检测HBVDNA、套式PCR检测HCVRNA、HGVRNA、TTVDNA。结果　 30例肝癌患者血清中单纯HBVDNA阳性率 (16 / 30 ) 5 3.3%、HCVRNA阳性率 (4 /30 ) 13.3%;二重感染HBVDNA、HCVRNA阳性率 (2 / 30 ) 6 .7%、HBVDNA、HGVRNA阳性率 (1/ 30 ) 3 3%、HBVDNA、TTVDNA阳性率 (10 / 30 ) 33.3%;HCVRNA、TTVDNA阳性率 (1/ 30 ) 3 3%、HCVRNA、HGVRNA阳性率 (1/ 30 ) 3 3%;三重感染HBVDNA、HCVRNA、HGVRNA阳性率 (1/ 30 ) 3 3%。结论　肝癌与肝炎病毒的感染有关 ,且存在较高比率的重叠感染 ,介入治疗中存在被感染的可能性 ,其预防十分重要。Objective To understand the infections of HBV HCV HGV TTV in patients with hepatocellular carcinoma (HCC), and to study the possibility and prevention of hepatitis transmission by blood in interventional treatment of HCC.Methods HBV DNA was detected by immune PCR and HCV RAN HGV RNA TTV DNA were detected by nest PCR.Results In 30 patients with HCC, the positive rate of HBV DNA 53.3%(16/30) HCV RNA 13.3%(4/30);the dual infectious rate of HBV DNA HCV RNA was 6.7%(2/30) HBV DNA and HGV RNA was 3.3%(1/30) HBV DNA and TTV DNA was 33.3%(10/30)? HCV RNA and TTV DNA was 3.3%(1/30)? HCV RNA and HGV RNA was 3.3%(1/30);the triple infection rate of HBV DNA HCV RNA HGV RNA was 3.3%(1/30).Conclusion HCC is related with hepatitis virus, it is possible to be affected in the interventional treatment of HCC and the prevention is very important.

关 键 词：乙肝病毒 丙肝病毒 庚肝病毒 TT病毒 重叠感染 介入治疗 肝癌 预防 

分 类 号：R735.7[医药卫生—肿瘤]