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作 者:刘晓华[1] 张钧寿[1] 李纯球[1] 陈晓然[1] 易建通[1]
机构地区:[1]中国药科大学,江苏南京210038
出 处:《中成药》2001年第12期859-862,共4页Chinese Traditional Patent Medicine
摘 要:目的 :考察中药制备结肠靶向给药的可能。方法 :药物提取 ,精制后 ,制成微丸 ,选取经特殊处理果胶为包衣材料 ,氯化亚铵作为放射性内标物。结果 :各项实验证明本制剂达到结肠靶向释药的设计要求。结论Objective:To study possibility of traditional Chinese drug preparation of controlled drug delivered to the colonic region. Methods: After the herbs was extracted and refined, micropills was produced with pectin selected as coating material and thallium monochloride was as internal standard substance. Results: The preparation was testified to attain schedule colon target. Conclusions: This research provided a way for traditional Chinese drug preparation of colon targeting.
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