中药结肠靶向给药研究  被引量:31

Study on Traditional Chinese Drug Colon Targeting System

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作  者:刘晓华[1] 张钧寿[1] 李纯球[1] 陈晓然[1] 易建通[1] 

机构地区:[1]中国药科大学,江苏南京210038

出  处:《中成药》2001年第12期859-862,共4页Chinese Traditional Patent Medicine

摘  要:目的 :考察中药制备结肠靶向给药的可能。方法 :药物提取 ,精制后 ,制成微丸 ,选取经特殊处理果胶为包衣材料 ,氯化亚铵作为放射性内标物。结果 :各项实验证明本制剂达到结肠靶向释药的设计要求。结论Objective:To study possibility of traditional Chinese drug preparation of controlled drug delivered to the colonic region. Methods: After the herbs was extracted and refined, micropills was produced with pectin selected as coating material and thallium monochloride was as internal standard substance. Results: The preparation was testified to attain schedule colon target. Conclusions: This research provided a way for traditional Chinese drug preparation of colon targeting.

关 键 词:中药 结肠靶向 果胶 靶向给药 

分 类 号:R283.6[医药卫生—中药学]

 

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