中药水蛭经炮制后的成分变化研究  

Variations of Chemical Compositiion of Leech(Scalded)

作　　者：刘丽芳[1] 金蓉鸾[1] 徐国钧[1] 吴子斌[2] 

机构地区：[1]中国药科大学,江苏南京210038 [2]香港中文大学生化系

出　　处：《中成药》2001年第12期880-882,共3页Chinese Traditional Patent Medicine

摘　　要：目的 :探讨水蛭经炮制后的化学成分变化情况 ,为水蛭的炮制方法提供一定的化学依据。方法 :采用HPLC 柱后衍生化法测定了氨基酸组成的变化 ,用GC MS法测定了甾体类化合物组成的变化。结果 :水蛭经炮制后各种氨基酸的量有所降低 ,甾体类化合物组成发生了变化。结论Objective:To provide chemical basis for processing of leech through investigating the variations of composition of leech scalded with talc powder. Methods: Amino acids were determined by HPLC post column derivatization and steroids by GC MS. Results: The results showed the total contents of amino acids in scalded leech were reduced and the steroids of it were changed. Conclusion: The processing method of leech used at the moment has a great influence in chemical components of leech.

关 键 词：中药水蛭 炮制 氨基酸 甾体类化合物 

分 类 号：R282.740.2[医药卫生—中药学]