肺癌介入治疗中药物灌注问题的模拟研究  

A Simulation Study on the Drug Injection for Interventional Treatment of Lung Cancer

作　　者：袁华[1] 岑人经[1] 吴效明[1] 袁支润[2] 贺继刚[3] 

机构地区：[1]华南理工大学生物力学研究所,广州510640 [2]四川大学生物力学研究所,610015 [3]广州军区武汉总医院介入治疗科,430070

出　　处：《实验力学》2001年第4期396-401,共6页Journal of Experimental Mechanics

基　　金：国家自然科学基金资助项目 ( 1 9972 0 4 4);广东省自然科学基金资助项目 ( 990 6 6 8)

摘　　要：本文用模拟实验方法探讨了临床肺癌介入治疗中的药物灌注问题 .对血流自然灌注区给出了新的定义 ,应用 p H值测定法对自然灌注区的形状进行了测定 .获得了介入导管端口的最佳放置位置 ,求出了药物灌注量和介入导管端口位置的关系以及药物灌注率和药液注射速度的关系 .Drug injection technique used in interventional treatment of lung cancer are studied. A new definition for the region of natural migration is given. The form of natural migration region is tested by using a pH method. The optimum position in which the end of interventional catheter is placed, as well as the influence of the position for the end of the interventional catheter and the injection speed of drug liquid on injection effectiveness are obtained. An effective principle for conducting the drug injection in the interventional treatment of lung cancer is proposed.

关 键 词：介入治疗 介入导管 肺癌 药物灌注 模拟实验 PH值测定 

分 类 号：R734.2[医药卫生—肿瘤] R730.55[医药卫生—临床医学]