胸腔镜胸膜剥除术加综合性治疗恶性胸水的疗效分析  

THERAPEUTIC EFFECTS OF VIDEO-ASSISTED THORACOSCOPIC PLEURECTOMY PLUS MULTIMODALITY THERAPY ON MALIGNANT PLEURAL EFFUSION

作　　者：谷力加[1] 吴一龙[1] 翁毅敏[1] 冯卫能[1] 程超[1] 黄邵洪[1] 程华[1] 

机构地区：[1]中山医科大学附属第三医院胸心外科,广州510630

出　　处：《中国内镜杂志》2001年第5期1-2,共2页China Journal of Endoscopy

摘　　要：目的 :探讨胸腔镜胸膜剥除术加综合性治疗恶性胸水的临床疗效。方法 :应用电视胸腔镜技术施行 2 1例恶性胸水的胸膜剥除术 ,术中用顺铂 2 0mg加注射用水 2 0 0ml冲洗胸腔 ,术后再辅以局部 2～ 3周期和全身 4个周期化疗的综合性治疗 2 1例肺内、外肿瘤并恶性胸水病人。治疗完成后 ,参考WHO近期疗效评价标准和生存质量KPS评分标准进行评价。结果 :随访率 10 0 % ,胸水完全缓解率为 90 .5 % ,有效率 10 0 %。自觉症状均得到明显改善 ,治疗后KPS评分较治疗前均提高 2 0分以上 ,有显著性差异 ,P <0 .0 5。生存期超过 6个月以上 2 0例。结论Objective:To study the clinical effect of video-assisted thoracoscopic pleurectomy plus multimodality therapy for malignant leural effusion.Method:21 patinets who suffered from malignant pleural effusion was performed with the pleurectomy with the minimally invasive technique of thoracopscopy and was douched in t he thoracic cavity during operation with the liquid of 100ml water for injection and 20 mg cispatin.All the patients was received the local chemotherapy for two or three courses and general chemotherapy for four courses in the measures of multimodality therapy of malignant pleural effusion after opertation.The outcome was evaluated with evaluation stadard of recent treament effect of WHO and survival ualtiy of KPS.Results:Follow-up survery rate was 100%.All sbjective symtoms were improved.The complete remission rate of hydrothorax was 90.5%.The response rate was 100%.The fraction of KPS was increased over 20 marks after operation.significance test P <0.05.Survival stage of 10 cases was beyong 6 month.Conclusions:The mode of video-assisted thoracosocpic pleurectomy plus multimodatlity therapy with local and general chemotherapy for malignant pleural effusion can increase effectively the survival quality and prolong survival time.

关 键 词：胸腔镜术 恶性胸水 综合治疗 

分 类 号：R734.205[医药卫生—肿瘤] R730.58[医药卫生—临床医学]