N-苯基-N′-(1,2,3-噻二唑-5-基)脲生成反应的热化学性质研究  

Research for the Thermochemical Properties of the Formation Reaction of -N-Phenyl-N′-(1,2,3-thiadiazol-5-yl)urea

作　　者：孙晓红[1] 刘源发[2] 高胜利[2] 张晓玉[2] 

机构地区：[1]西北大学化学研究所化工系,西安710069 [2]西北大学化学研究所化学系,西安710069

出　　处：《高等学校化学学报》2002年第3期361-363,共3页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金 (批准号 :2 98710 2 3 );陕西省教委重点科研项目 (批准号 :99JK0 9)资助

摘　　要：The enthalpy change of formation reaction of the \%N\%\|phenyl\|\%N\%\+′\|(1,2,3\|thiadiazol\|5\|yl)urea has been determined by a microcalorimeter, using 5\|amino\|1,2,3\|thiadiazole and phenylisocyanate as starting materials in the solvent of THF. The reaction temperature was kept at 25 ℃. On the basis of experimental and calculated results, the enthalpy change is Δ\-r\%H\%\+\{o-\}\-m=(-142.304±0.390) kJ·mol\+\{-1\}; the reaction order is \%n\%=1/2; the rate constant \%k\%=1.357 9×10\+\{-4\} s\+\{-1\} and the activation free\|energy is Δ\%G\%\+\{o-\}\-m=95.098 \{kJ·mol\+\{-1\}\}. The result indicates that the title reaction takes place easily at room temperature.The enthalpy change of formation reaction of the \%N\%\|phenyl\|\%N\%\+′\|(1,2,3\|thiadiazol\|5\|yl)urea has been determined by a microcalorimeter, using 5\|amino\|1,2,3\|thiadiazole and phenylisocyanate as starting materials in the solvent of THF. The reaction temperature was kept at 25 ℃. On the basis of experimental and calculated results, the enthalpy change is Δ\-r\%H\%\+\{o-\}\-m=(-142.304±0.390) kJ·mol\+\{-1\}; the reaction order is \%n\%=1/2; the rate constant \%k\%=1.357 9×10\+\{-4\} s\+\{-1\} and the activation free\|energy is Δ\%G\%\+\{o-\}\-m=95.098 \{kJ·mol\+\{-1\}\}. The result indicates that the title reaction takes place easily at room temperature.

关 键 词：N-苯基-N′-(1 2 3-噻二唑-5-基)脲 生成反应 热化学性质 细胞分裂激素 合成 微热量计 热动力学 焓变 

分 类 号：TQ452[化学工程—农药化工] O642.3[理学—物理化学]