轻度认知损害患者情节记忆的编码和提取  

Encoding and retrieval of episodic memory in patients with mild cognitive impairment

作　　者：汪青松[1] 许浩[1] 秦松[2] 赵卉[2] 吴颖惠[2] 黄永璐[2] 周江宁[1] 

机构地区：[1]中国科学技术大学生命科学学院神经生物学系神经退行性疾病研究室,安徽合肥230027 [2]安徽医科大学第一附属医院安徽老年病研究所,安徽合肥230001

出　　处：《中国神经科学杂志》2002年第1期451-453,共3页

基　　金：国家 973计划资助项目 (G19990 0 5 4)

摘　　要：为了研究轻度认知损害患者情节记忆编码和提取的改变 ,采用神经心理学方法评定正常老年人和轻度认知损害患者 (MCI)情节记忆编码和提取。结果表明 :除存在记忆力损害以外 ,MCI组定向力、语言能力、执行等能力显著低于正常老年组 (P <0 .0 1) ;MCI组患者情节记忆编码正确率显著低于正常老年组 (P <0 .0 1) ,下降约2 2 .81% ;MCI组情节记忆提取正确率显著低于正常老年组 (P <0 .0 5 ) ,下降约 6 .84 %。提示轻度认知损害患者情节记忆编码和提取均存在不同程度的损害 ,而情节记忆编码的损害更明显。To investigate retrieval and encoding of episodic memory in patients with mild cognitive impairment (MCI), neuropsychologic methods were used. We found that there was significant decline in the function of orientation, language and praxis besides memory impairment in MCI group. In MCI group significant decrease of encoding and retrieval was also observed, there was about 6.84% decrement in retrieval of episodic memory and 22.8% decrement in encoding of episodic memory. It is suggested that there is encoding and retrieval impairment of episodic memory in MCI and that encoding of episodic memory is more vulnerable to be impaired. \[

关 键 词：编码 提取 情节记忆 轻度认知损害 神经心理学 AD病 

分 类 号：R749.161[医药卫生—神经病学与精神病学]