云南傈僳和布依族六个基因座的遗传多态性分析  

Distribution of 6 Loci in Lisu and Bouyei Minority Populations in Yunnan Province of China

作　　者：李德林[1] 邹苹[2] 邹浪萍 李建京[1] 杨燕[2] 申滨[1] 

机构地区：[1]昆明医学院,昆明650031 [2]昆明市妇幼保健院,昆明650031 [3]云南省高级人民法院司法鉴定科学技术研究所,昆明650021

出　　处：《昆明医学院学报》2002年第1期35-38,共4页Journal of Kunming Medical College

基　　金：国家自然科学基金 (3976 0 0 35 )

摘　　要：短串联重复序列 (STR)是由几个碱基对作为核心单位串联重复形成的一类DNA序列 .该文应用CSF1PO ,TPOX ,TH0 1,F13A0 1,FESFPS和vWA 6个基因座在两个反应体系中进行互不干扰的多重PCR ,采用高分辨力的聚丙烯酰胺凝胶电泳分离、银染法显影技术 ,对云南省傈僳族和布依族两个少数民族的上述6个基因座等位基因的基因频率分布进行了调查 ,获得了满意的结果 。The short tandem repeats is a kind of DNA sequence formed repeatedly and connected by several base pairs as a core unit. The non-interfered multi-PCR was applied to 6 loci in the halve reaction system. By using the technique of denaturing polyacrilamid gel electrophoresis and silver stain, the allele frequency distributions of 3 loci: CSF1PO, TPOX ,THO1, F13A01 ,FESFPS and vWA in 2 minority populations resided in Yunnan Province: Lisu and Bouyei were investigated. A satisfactory result was obtained and some significant genetics differences were noticed in different populations.

关 键 词：CSF1PO TPOX TH01 F13A01 FESFPS vWA 傈僳族 布依族 云南 基因座 遗传多态性 

分 类 号：Q346.5[生物学—遗传学]