后基因组时代药理学研究趋向  

Trends in the Post-genomic Pharmacological Research

作　　者：魏尔清[1] 沈建中[1] 

机构地区：[1]浙江大学医学院药理学教研室,杭州310031

出　　处：《生理科学进展》2002年第1期7-11,共5页Progress in Physiological Sciences

基　　金：国家重点基础研究发展规划 (973)项目G19990 5 40 0 3子课题资助

摘　　要：药理基因组学 (药物基因组学 ,pharmacogenomics)将成为后基因组时代药理学研究的新领域。与此相应 ,高通量筛选 (high throughputscreening ,HTS)、insilico研究以及多种功能可视化技术已开始成为药理学研究的新方法。本文同时介绍上述新思路与新方法应用于药效学。With the advent of post genome era, pharmacogenomics will be a new field in pharmacological sciences. In parallel, high throughput screening, in silico research, as well as lots of visualization techniques are emerging as novel approaches in pharmacological researches. Some progress in the implementation of aforementioned new idea and methods in pharmacodynamics and pharmacokinetics research are also introduced in this review.

关 键 词：药理基因组学 高通量筛选 药效学 后基因组时代 药动学 研究方向 

分 类 号：R96[医药卫生—药理学]