红细胞CR1分子定量测定在细菌L型败血症中的意义  

CLINICAL IMPLICATIONS OF QUANTITATIVE ASSAY FOR COMPLEMENT RECEPTOR 1 ON ERYTHROCYTES IN PATIENTS WITH SEPSIS INDUCED BY BACTERIA L FORMS

作　　者：张伊莉[1] 潘立民[1] 王恩举[1] 李莹[1] 卞建军[1] 

机构地区：[1]蚌埠铁路分局中心医院内科,安徽蚌埠233040

出　　处：《医师进修杂志》2002年第3期18-19,共2页Journal of Postgraduates of Medicine

摘　　要：目的　探讨细菌L型败血症 (SBL)患者红细胞CR1分子定量的变化。方法　采用王海滨、郭峰等创立的测定完整红细胞膜分子的酶免疫定量方法 ,对 5 3例SBL患者及 5 6例健康人测定比较。结果　红细胞CR1分子(CD3 5)SBL组较健康对照组低 ,有非常显著的差异 (P <0 .0 0 1) ,SBL组发病期与恢复期比较也有非常显著差异 (P<0 .0 0 1)。结论　SBL组发病期CR1有不同程度地减少 ,病情恢复后 ,CR1上升 ,与疾病的转归相关。Objective\ To investigate variations of complement receptor 1 on erythrocytes in patients with sepsis-induced by bacteria L forms.Method\ The erythrocyte enzyme immunization method quantitatively assaying complete erythrocyte CR1 invented by Wang Haibin and Guo Feng was applied to test 53 patients and 56 healthy subjects.Results\ The erythrocyte CR1 molecules (CD_ 35 ) of patient group are significantly lower than that of the healthy group and the difference was very significant (P <0.001).The morbidity and coalescence period of the patient group also varied greatly (P <0.001).Conclusion\ CR1 during sepsis were decreased and after recovery CR1 increased,it is closely related to the changes of diseases.

关 键 词：红细胞 CR1分子定量 细菌L型败血症 测定 败血症 

分 类 号：R515.3[医药卫生—内科学]