氯氮平与利培酮对精神分裂症病人生活质量影响的双盲对照研究  

Comparison of Quality of Life of Schizophrenic Outpatients Treated with Risperdal or Clozapine

作　　者：任清涛[1] 路英智[1] 田明萍[1] 蔡大庆[1] 

机构地区：[1]山东省淄博市精神病医院,255100

出　　处：《中国心理卫生杂志》2002年第3期199-199,198,共2页Chinese Mental Health Journal

摘　　要：目的 :观察氯氮平与利培酮治疗对精神分裂症病人生活质量的影响。方法 :双盲对照研究。用阳性症状与阴性症状评定量表 (PANSS)观察病人的精神症状 ,用生活质量综合评定问卷 (GQOLI)分析病人生活质量。结果 :利培酮组的躯体健康维度、心理健康维度及社会功能维度得分明显高于氯氮平组 ,均有显著性差异 (P <0 0 1)。结论 :利培酮组精神分裂症病人生活质量优于氯氮平组。Objective: To compare the influences of clozapine and risperdal on quality of life of schizophrenics Method: Double blinded randomized study was done in 120 schizophrenic outpatients (60 in each group) GQOLI (general quality of life inventory) and PANSS (positive and negative symptom scale) were used as research instruments Results: The risperdal group had better results in physical function, mental health and social function than clozapine (P<0 01) Conclusion:Schizophrenic outpatients treated with risperdal has better quality of life than those with clozapine

关 键 词：氯氮平 利培酮 精神分裂症 生活质量 双盲对照研究 

分 类 号：R749.3[医药卫生—神经病学与精神病学] R971.4[医药卫生—临床医学]