腹泻型肠易激综合征患者肛门直肠动力的探讨  

The functional changes of anorectal motility in diarrheic patients with irritable bowel syndrome

作　　者：蔡联英 梁荣新 梁列新 

机构地区：[1]广西区人民医院消化内科,530021

出　　处：《广西医学》2002年第3期301-302,共2页Guangxi Medical Journal

基　　金：广西留学回国人员科学基金资助 (桂科回 992 0 0 13 )

摘　　要：目的 :探讨肠易激综合征 (IBS)患者肛门直肠运动功能的变化。方法 :对 2 4例腹泻型肠易激综合征患者、14例正常人采用液导法进行直肠肛管压力测定 ,用持续气囊扩张法进行直肠敏感性检测。结果 :腹泻型肠易激综合征患者直肠静息压、直肠外括约肌静息压力、直肠内括约肌静息压力、外括约肌最大缩窄压、内括约肌最大缩窄压 (分别为 2 2± 0 81kPa、8 6 4± 2 7kPa、4 3± 1 4kPa、2 2± 5kPa、9 4± 2 3kPa)与正常组 (9 2± 1 4kPa、5 2± 2 2kPa、1 1± 0 5kPa、2 4± 6kPa、12 9± 4 5kPa)相似(P >0 0 5 )。但直肠最低敏感量、有便意时的气囊容积、便意窘迫时的气囊容积及最大耐受容积 (34± 19ml、74± 2 4ml、12 5±6 4ml和 16 4± 5 2ml)均显著低于正常对照组 (84± 4 8ml、10 4± 5 2ml、2 0 4± 6 9ml、2 5 4± 74ml) (P <0 0 5 )。结论 :IBS患者症状的产生可能与直肠肛管的机械压力无关 。Objective:To study the funtional change of anorectal motility in patients with irritable bowel syndrome(IBS).Methods:Rectal visceral perception thresholds and anorectal manometry were determined in 24 diarrheic patients with IBS and 14 healthy volunteers by means of lasting balloon distention and perfusion catheter manometer.Result:1.In the diarrheic patients with IBS,the static pressure of rectum,the static pressure and maximal squeeze pressure of external and internal sphincter were(1 3±0 8)kPa,(8 64±2 7)kPa,(4 3±2 3)kPa,(22±5)kPa and (9 4±2 3)kPa respectively,which were similar to those of normal volunteers(9 2±1 4kPa,5 2±2 2kPa,1 1±0 5kPa,24±6kPa and 11 3±4 5kPa)(P>0 05).2.The rectal lowest sensory threshold(RLSTV),the rectal lowest and maximal volume of awareness of defecation and the rectal maximal volume tolerance(24±8ml,74±24ml,125±64ml and 164±52ml)were lower than those in healthy voluteers(34±18ml,104±52ml,204±69ml,254±74ml)(P<0 05).Conclusions:The results suggest that the symptions of patients with IBS are not associated with anorectal motility,the hight rectal sensivity might play an important role on it.

关 键 词：结肠疾病 功能性 直肠 腹泻型肠易激综合征 

分 类 号：R574.4[医药卫生—消化系统] R574.62[医药卫生—内科学]