肿瘤免疫治疗成像技术的研究进展  

Advances in imaging technologies for cancer immunotherapy

作　　者：许金霞 唐建斌[2] XU Jinxia;TANG Jianbin(Department of Radiology,The Children's Hospital,Zhejiang University School of Medicine,Hangzhou 310003,Zhejiang Province,China;Center for Bionanoengineering,College of Chemical and Biological Engineering,Zhejiang University,Hangzhou 310027,Zhejiang Province,China)

机构地区：[1]浙江大学医学院附属儿童医院放射科,浙江杭州310003 [2]浙江大学化学工程与生物工程学院生物纳米工程中心,浙江杭州310027

出　　处：《肿瘤影像学》2018年第5期426-430,共5页Oncoradiology

基　　金：国家自然科学基金委优秀青年基金项目(51522304);国家自然科学基金面上项目(21774109)

摘　　要：由于传统的影像学技术难以满足肿瘤免疫治疗的临床需求,目前亟待开发新的免疫影像学技术来示踪免疫细胞和评价免疫治疗效果。本文综述了免疫PET、CT、MRI、光学成像及多模式成像的最新研究进展,虽然基于各种新型探针的免疫成像技术获得了巨大进步,但是仍需进一步验证它们的安全性和有效性,才能获得可进入临床应用的免疫成像技术。Since the traditional imaging technologies cannot meet the demands from immunotherapy,new imaging technologies are highly desired to track immune cells and evaluate the efficacy of immunotherapy.This review summarizes the advances in PET, CT,MR/,optical and multimodal imaging for cancer immunotherapy.A large number of new imaging technologies with novel probes have been reported for immunotherapy,but further research needs to be done to validate their safety and effectiveness before they enter into clinical applications.

关 键 词：肿瘤 免疫治疗 影像技术 生物探针 

分 类 号：R730.51[医药卫生—肿瘤]