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作 者:George Kassimis Tushar Raina
机构地区:[1]Department of Cardiology,Cheltenham General Hospital,Gloucestershire Hospitals NHS Foundation Trust,Cheltenham,United Kingdom [2]Second Department of Cardiology,Hippokration Hospital,Medieal School,Aristotle University of Thessaloniki,Thessaloniki,Greece
出 处:《Journal of Geriatric Cardiology》2018年第10期639-643,共5页老年心脏病学杂志(英文版)
摘 要:Compared with bare-metal stents (BMS),drug-eluting stems (DES)have shown better clinical outcomes for pa- tients undergoing percutaneous coronary intervention (PCI) by inhibition of neo-intirnal hyperplasia.[1]However,early- generation DES produced late thrombotic events,more than l-year,by delaying arterial healing of stented vessels,[2-5] New-generation DES have been developed'with thinner stent struts,more biocompatible polymer coatings for drug release,and a variety of antiproliferative agents with similar or superior anti-restenotic efficacy.[6]This development has led to a significant improvement in the efficacy and safety of new-generation DES,and consistently lower rates of very late stent thrombosis (VLST).[7,8]In fact,use of new-ge- neration DES is the standard treatment in contemporary PCI practice.[9]
关 键 词:DOUBLE VESSEL occlusion Myocardial infarction Very late stent thrombosis ZOTAROLIMUS eluting STENTS
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