纳米技术在癌症预防、诊断和治疗中的应用研究进展  

Application of nanotechnology in cancers prevention,diagnose and treatment

作　　者：汪超[1] 范亲 顾臻[2] 刘庄[1] WANG Chao;FAN Qin;GU Zhen;LIU Zhuang(Institute of Functional Nano &Soft Materials (FUNSOM),Suzhou215123,China;Department of Bioengineering,University of California,Los Angeles 90095,USA)

机构地区：[1]苏州大学功能纳米与软物质研究院,苏州215123 [2]加利福尼亚大学洛杉矶分校生物工程系,洛杉矶90095

出　　处：《科技导报》2018年第22期96-107,共12页Science & Technology Review

摘　　要：癌症是威胁人类健康的重大疾病之一,是当前人类所面临的重要挑战。将功能性纳米材料及相关体系用于癌症治疗是目前的研究热点,主要涉及药物递送系统、疫苗、诊断和成像等领域。目前,部分成果已经进入临床或临床前研究阶段,为实时监测、准确评估及制定个性化治疗方案提供了可能。综述了近年来纳米技术在肿瘤预防、诊断、治疗、诊疗一体化及临床转化方面的研究进展,探讨了纳米技术在未来发展中的前景及挑战。Cancer,as the one of the major diseases that threaten human health is an urgent challenge to be addressed.The design and application of functional nanomaterials and related systems for cancer treatment is an emerging research field,mainly associated with drug delivery systems,vaccine,diagnosis and imagining.To date,some of these outcomes could be seen in the clinical and preclinical studies, which provides the possibility for real-time monitoring,accurate evaluation and designation of personalized treatment.Here,we review the recent progress of utilizing nanotechnology in the field of cancer prevention,diagnosis,treatment,theranostics and clinical transformation.The prospects and challenges of this field are also discussed.

关 键 词：纳米技术 分子影像 诊断治疗 药物递送 纳米疫苗 

分 类 号：TB383.1[一般工业技术—材料科学与工程] R730[医药卫生—肿瘤]