成人OSAHS患者认知功能障碍及血清生化指标改变的研究进展  

Advances in cognitive impairment and serum biochemical markers in adult patients with obstructive sleep apnea-hypopnea syndrome

作　　者：金玉波 何晓光[1] 

机构地区：[1]昆明医科大学第一附属医院耳鼻咽喉二科,云南昆明650000

出　　处：《中国医学文摘（耳鼻咽喉科学）》2018年第6期496-499,共4页Chinese Medical Digest(Otorhinolaryngology)

摘　　要：随着生活质量的改善、肥胖人数的增多以及人口的老龄化,阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)的发病率不断增加,且随着人们对生活质量的要求提高,其继发引起的认知功能障碍及OSAHS合并认知功能障碍患者的血清学研究也越来越引起耳鼻喉科医生的关注,现对OSAHS继发引起认知功能障碍患者的血清相关生化指标的改变做一综述。With the improvement of quality of life,the increase of obesity and the aging of the population,the incidence of obstructive sleep apnea hypopnea syndrome (OSAHS)is increasing,and with the improvement of people's quality of life,the secondary cognitive dysfunction and OSAHS combination are caused.The serological study of patients with cognitive impairment has attracted more and more attention of otolaryngologists.This article reviews the changes of serum biochemical indexes in patients with OSAHS secondary cognitive impairment.

关 键 词：阻塞性睡眠呼吸暂停低通气综合征 认知功能 S100Β蛋白 脑源性神经营养因子 5-羟色胺 

分 类 号：R749.16[医药卫生—神经病学与精神病学]