经直肠前列腺穿刺活检中应用不同针径活检针的对比研究  

Comparative study of different diameter biopsy needles in transrectal prostate biopsy

作　　者：吴万文[1] 吕蔡[1] 刘振湘[1] 白志明[1] WU Wanwen;LV Cai;LIU Zhenxiang;BAI Zhiming(Department of Urology,Affiliated Haikou Hospital of Xiangya Medical School Central South University,Haikou,570208,China)

机构地区：[1]中南大学湘雅医学院附属海口医院泌尿外科,海口570208

出　　处：《临床泌尿外科杂志》2018年第12期1000-1002,共3页Journal of Clinical Urology

基　　金：海南省卫生厅科研课题(编号2012PT-48);海口市重点科技计划课题(编号2012-081)

摘　　要：目的:比较不同针径活检针在超声引导下经直肠前列腺穿刺活检中的应用价值。方法:选取2015年1月～2016年10月在我院泌尿外科行超声引导下经直肠前列腺穿刺活检患者100例,采用随机数表法将患者分为观察组与对照组,每组50例,观察组采用16G活检针,对照组采用常规18G活检针,两组均进行相同的系统12针+靶向穿刺方案,由同一名专职医师完成穿刺操作。比较两组间穿刺阳性率以及术后并发症发生率。结果:两组12针系统穿刺阳性率比较差异无统计学意义(36%vs.24%,P=0.190),而靶向穿刺阳性率比较观察组优于对照组(37.5%vs.15.0%,P=0.022)。观察组穿刺阳性率与血清总PSA水平、PSA密度有相关性。两组术后疼痛评分(P=0.629)、术后并发症发生率(P=0.648)比较差异无统计学意义。结论:16G活检针能显著提高前列腺靶向活检阳性率,且术后相关并发症风险并未增加。Objective:To compare the application value of different diameter biopsy needles in transrectal prostate biopsy under ultrasound guidance.Method:One hundred patients undergoing transrectal prostate biopsy under ultrasound guidance from January 2015 to October 2016 were enrolled in our department.The patients were divided into observation group and control group by random number table method,50 cases in each group.The observation group used a 16 Gbiopsy needle,while the control group used a conventional 18 G biopsy needle.Both groups performed the same system 12-needle+targeted puncture protocol,and the same physician completed the puncture operation.The positive rate of puncture between the two groups and the incidence of postoperative complications were compared.Result:There was no significant difference in the positive rate of 12-needle system puncture between the two groups(36%vs.24%,P=0.190),but the positive rate of targeted puncture in the 16 Gbiopsy group was better than that of the 18 Gbiopsy group(37.5%vs.15.0%,P=0.022).There was a correlation between the positive rate of puncture and the total serum PSA level and PSA density in the 16 Gbiopsy group.There was no significant difference in postoperative pain scores(P=0.629)or postoperative complications(P=0.648)between the two groups.Conclusion:Needle of 16 Gcan significantly improve the positive rate of prostate biopsy,and the risk of postoperative complications doesn’t increase.

关 键 词：16G活检针 18G活检针 经直肠前列腺穿刺活检 前列腺癌 安全性 

分 类 号：R737.25[医药卫生—肿瘤]