小肠胃肠道间质瘤的诊断及治疗进展  

Progress in diagnosis and treatment of gastrointestinal stromal tumors

作　　者：李洪涛 赵丽娟[1] 孙勇军[1] Li Hongtao;Zhao Lijuan;Sun Yongjun(Shengli Oilfield Central Hospital Dongying Shandong 257034 China)

机构地区：[1]胜利油田中心医院,山东东营257034

出　　处：《医药前沿》2018年第31期13-15,共3页Journal of Frontiers of Medicine

摘　　要：小肠胃肠道间质瘤是临床上最常见的消化道间叶肿瘤,以酪氨酸激酶受体KIT蛋白获得性突变为其特点,CT对其具有重大辅助诊断价值,病理联合免疫组化是确诊的金标准,早期局限型小肠GIST行手术完整切除预后良好,进展期小肠GIST需要手术联合伊马替尼等靶向药物综合治疗。近年来,对小肠胃肠道间质瘤的治疗趋于规范,极大改善了小肠GIST患者总体疗效及预后。本文联合国内外最新研究进展,对其临床特点、诊断及治疗的最新进展进行综述。Small intestine gastrointestinal stromal tumor is the most common gastrointestinal mesenchymal tumors,clinical KIT protein tyrosine kinase receptor acquired mutation as its characteristics,CT plays an important auxiliary diagnostic value for its disease pathology joint immunohistochemical is the gold standard for diagnosis,early limited line type small intestine GIST complete resection surgery prognosis is good,the advanced small intestine GIST require surgery combined imatinib targeted drugs such as comprehensive treatment,in recent years,the treatment of small intestinal gastrointestinal stromal tumor,tend to be standard,greatly improved the overall curative effect and prognosis in patients with small intestine GIST.In this paper,the latest advances in clinical features,diagnosis and treatment are reviewed.

关 键 词：小肠胃肠间质瘤 伊马替尼 临床诊断 治疗 

分 类 号：R735[医药卫生—肿瘤]