儿童颅内非典型畸胎瘤样/横纹肌样瘤的MR表现  

MR findings of children with intracranial atypical teratoid/rhabdoid tumors

作　　者：马桢[1] 程敬亮[1] 张勇[1] 汪卫建 任琦[1] MA Zhen;CHENG Jing-liang;ZHANG Yong;WANG Wei-jian;REN Qi(Department of MRI,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院磁共振科,河南郑州450052

出　　处：《中国临床医学影像杂志》2018年第12期848-851,880,共5页Journal of China Clinic Medical Imaging

摘　　要：目的:探讨颅内非典型畸胎瘤样/横纹肌样瘤(AT/RT)的影像表现特征。资料与方法:对2013年11月—2017年1月6例经病理和免疫组化诊断为AT/RT患者的临床及MRI(n=6)影像资料进行回顾性分析。男5例,女1例,年龄1～7岁,中位年龄1.25岁。6例均行MR平扫及增强检查。结果:6例AT/RT患者中4例肿瘤位于幕下,1例位于幕上,1例幕上及幕下多发病灶,肿瘤最大径为2.0～4.6 cm,6例肿瘤合并囊变5例、出血4例,所有病灶都呈中重度强化。DWI呈不均匀高信号,ADC呈低信号。其中有1例发生脑脊液播散,1例术后出现脑转移。结论:颅内AT/RT具有一定特征性的影像学表现,有助于鉴别诊断。Objective:To evaluate the imaging characteristics of intracranial atypical teratoid/rhabdoid tumor (AT/RT),and to improve the diagnostic ability of the disease.Materials and Methods:The clinical and MRI (n=6)imaging findings of 6 patients with AT/RT diagnosed by pathology and immunohistochemistry were analyzed retrospectively.There were 5 male and 1 female,aged 1year to 7years,median age was 1.25 years.MR enhancement studies were obtained in all the cases.Results: Among 6 patients with AT/RT,4 were located below the tentorium,1was located supratentorial,and 1was multiple lesions both supratentorial and subtentorial.The tumors'size varied from 2.0cm to 4.6cm.Cystic change was seen in 5 cases and hemorrhage in 4 cases.All lesions showed moderate to severe enhancement.Diffused-weighted imaging demonstrated inhomogeneous signal and ADC showed low signal.Cerebrospinal fluid dissemination occurred in 1case,and brain metastasis occurred in 1case.Conclusion:There are some relatively specific imaging findings of primary intracranial AT/RT that could assist their diagnosis.

关 键 词：脑肿瘤 肿瘤 生殖细胞和胚胎性 儿童 磁共振成像 

分 类 号：R739.41[医药卫生—肿瘤] R445.2[医药卫生—临床医学]