局部进展期和晚期胃癌化疗的临床应用及进展  

Advances of Chemotherapy for Patients with Locally Advanced and Advanced Gastric Cancer

作　　者：李孝远[1] 赵林[1] LI Xiao-yuan;ZHAO Lin(Peking Union Medical College Hospital ,Beijing 100032,China)

机构地区：[1]北京协和医院

出　　处：《肿瘤学杂志》2018年第12期1159-1164,共6页Journal of Chinese Oncology

基　　金：中国抗癌协会基金(CORP-143-09);北京协和医院中青年科研基金(PUMCH-2016-1.13)

摘　　要：胃癌在全球是癌症患者的重要死因,局部进展期和晚期胃癌患者预后差。(新)辅助化疗或化放疗在局部进展期胃癌治疗中获得广泛认可,姑息化疗仍是晚期胃癌的重要治疗手段。全文基于大量临床研究的证据进行综述,以更深入认识化疗的临床应用和进展,更好地指导胃癌的临床实践策略。Gastric cancer remains a leading cause of cancer-related mortality worldwide. The prognosis for patients with locally advanced or metastatic disease is poor. A multimodal approach to treatment with (neo) adjuvant chemotherapy or chemoradiotherapy has therefore been accepted to treat locally advanced gastric cancer.Palliative chemotherapy is still major therapy choice for metastatic gastric cancer.A number of clinical trials are ongoing,which seek to directly compare treatment options. This review will browse current evidences and strategies of gastric cancer treatment and hope to provide clarity and guide management in this area.

关 键 词：胃肿瘤 晚期 药物疗法 

分 类 号：R735.2[医药卫生—肿瘤]